RESEARCH

Staff

1. Phytochemical profiling and anti-inflammatory activity of Gentiana lutea roots from Pollino National Park

Authors: Giuseppe Falcone; Giacomo Di Matteo; Luisa Mannina; Francesco Cellini; Luigi Menghini; Simone Carradori; Ali Al-Samydai; Annalisa Chiavaroli; Simonetta Cristina Di Simone; Claudio Ferrante

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2. Therapeutic potential of marine sponges and nanoparticles: A study on siphonochalina siphonella and AgNPs

Authors: Moath Alqaraleh; Khaled M. Khleifat; Ali Al-Samydai; Futoon Abedrabbu Al-Rawashdeh; Belal O. Al-Najjar; Fadi G. Saqallah

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3. Bioactive potency of extracts from Stylissa carteri and Amphimedon chloros with silver nanoparticles against cancer cell lines and pathogenic bacteria

Authors: Moath Alqaraleh; Khaled M. Khleifat; Ali Al-Samydai; Belal O. Al-Najjar; Fadi G. Saqallah; Yaseen T. Al Qaisi; Ahmad Z. Alsarayreh; Dana A. Alqudah; Abdulfattah S. Fararjeh

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4. Novel Anticancer Triple Formula Based on Aptamer-Conjugated PEGylated Nanoliposomes

Authors: Ali Al-Samydai, PhD; Hamdi Nsairat, PhD; Moath Alqaraleh, PhD; Maha N. Abu Hajleh, PhD; Areej Jaber, PhD; Lidia Al-Halaseh, PhD; Hanan Azzam, MS; Qasim Khalid Alazzawi, PhD; Israa Al-Ani, PhD; Simone Carradori, PhD; Walhan Alshaer, PhD

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5. Enhancing surface quality and strength of QH21 magnesium alloy via friction stir processing with TiO₂–ZnO coatings: a Taguchi optimization approach

Authors: Ali Al-Samydai; Sathish Thanikodi; Jayant Giri; Saravanan Rathinasamy; Faouzi Nasri; A. Anderson

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6. A phytotherapeutic approach to hinder the resistance against clindamycin by MRSA: in vitro and in silico studies

Authors: Amal Mayyas; Ali Al-Samydai; Nehaya Al-Karableh; Waleed A Zalloum; Deniz Al-Tawalbeh; Farah Al-Mamoori; Rula A. Amr; Hamdi Al Nsairat; Simone Carradori; Lidia Kamal Al-Halaseh; Talal Aburjai

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7. Optimized Rutin-incorporating PEGylated Nanoliposomes as a Model with Remarkable Selectivity Against PANC1 and MCF7 Cell Lines

Authors: Ali Al-Samydai; Moath Al Qaraleh; Lidia K. Al-Halaseh; Maha N. Abu Hajleh; Simone Carradori; Maryam Abdulmaged; Rand Kareem; Hasanain Alzaidi; Mohamad AK. Mousa; Yusuf Al-Hiari; Hamdi Nsairat; Walhan Alshaer

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8. Use of complementary and alternative medicine among females with polycystic ovary syndrome in Jordan: a cross-sectional study

Authors: Oriana Awwad; Mais Saleh; Sanaa K Bardaweel; Ali Alsamydai; Fatma U Afifi; Amal Akour; Renad Abu Tarboosh; Manar Hamdan; Asma Sa’d Basha

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9. Chemical composition, antioxidant, and enzyme inhibition activities of Crithmum maritimum essential oils: the first chemo-biological study for species grown in North Africa

Authors: Ahmed Ismail; Fatma A. El-Shibani; Hamdoon A. Mohammed; Belal O. Al-Najjar; Amany M. Korkor; Abdulnaser Kh. Abdulkarim; Rana Said; Suliman A. Almahmoud; Ghassan M. Sulaiman

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10. New Chitosan-Based Trimetallic Cu₀.₅Zn₀.₅Fe₂O₄ Nanoparticles: Preparation, Characterization, and Anti-cancer Activity

Authors: Afnan Al-Hunaiti; Asma Ghazzy; Hazem Aqel; Tuqa Abu-Thiab; Ramzi Saeed; Mutasem Taha; Eman Hwaitat; Malek Zihlif; Amer Imraish

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11. Photocatalytic Polyaromatic hydrocarbons (PAH) utilizing magnetic CrFe₂O₄ nanoparticle: Green synthesis, characterization, ab initio studies, electronic, magnetic features and water treatment application

Authors: Afnan Al-Hunaiti; Asma M. Ghazzy; Nada T. Mahmoud

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12. Biological activities of Centaurium erythraea and its main chemotypes: menthol, carvacrol, and tricosane

Authors: Tarik Aanniz; Nasreddine El Omari; Saad Bakrim; Abdelaali Balahbib; Hamza Elhrech; Taoufiq Benali; Mohammed Amanullah; Long Chiau Ming; Said Moshawih; Abdelhakim Bouyahya

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13. Novel Diselenide Bis-Schiff bases tagged with diphenyl ethers: Promising candidates for selective treatment of hypopharyngeal and breast adenocarcinoma

Authors: Mohamed M. Hammouda; Saad Shaaban; Hussein Ba-Ghazal; Amal F. Dawood; Mohamed A. Zeidan; Arwa Omar Al Khatib; Fatema S. Alatawi; Khadra B. Alomari; Marwa Sharaky; Mohamed Alaasar; Ahmed A. Al-Karmalawy

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14. Ononin’s Antagonistic Activity towards TRPV1: Insights from Molecular Dynamics and Capsaicin-Evoked Calcium Response in DRG Neurons

Authors: Fadi G. Saqallah; Manal A. Abbas; Belal O. Al-Najjar; Aya Y. Al-Kabariti; Muhammad Yusuf; Omar A. Abdulwahed; Noor A. Barakat; Mohammad Alsalem

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Graduate Students

1. Novel glucokinase activators: A structure-based pharmacophore modeling, QSAR analysis, and molecular dynamics approach

Authors: Mansour Al-Sayed Ahmad, Belal O. Al-Najjar, Ashok Shakya

URL: View Article

2. Cytotoxic, anti-inflammatory, antioxidant, and anti-glyoxalase-I evaluation of chelating substances: In silico and in vitro study

Authors: Mohammed Bashar Al-Qazzan, Qosay Al-Balas, Belal Alnajjar, Violet Kasabri, Yusuf Al-Hiari, Aref Zayed, Rema AlKhateeb, Mohammed Al-Akeedi

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3. Rhoifolin potentiates the anti-cancer activity of doxorubicin in MDA-MB-231 triple-negative breast cancer cells

Authors: Ahmad Saleh Al-Radaideh, Manal A. Abbas, Aya Y. Al-Kabariti, Moath Alqaraleh, Razan Madi, Razan Obeidat

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4. Codelivery of Raloxifene and Rutin as PEGylated Nanoliposomes: Formulation, Characterization, and Prophylactic Activity Against Breast Cancer

Authors: Maryam Abdulmaged Oleiwi, Ali Al-Samydai, Aya Y. Al-Kabariti, Khaldun M. Al Azzam, Simone Carradori, Walhan Alshaer

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5. Preparation, characterization and in vitro evaluation of 5-fluorouracil loaded into chitosan–acacia gum nanoparticles

Authors: Hasan Al-Nasrawi, Naeem Shalan, Bassam M. Abualsoud, Hamdi Nsairat

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6. Green synthesized Zingiber officinale-ZnO nanoparticles: anticancer efficacy against 3D breast cancer model

Authors: Ruqaya Alhaddad, Bassam M. Abualsoud, Ibrahim Al-Deeb, Hamdi Nsairat

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7. HPLC Method Development and Validation for Metformin and Phenyl Butyric Acid and In Vitro Evaluation of Their PEGylated Liposomal Formulation Against Colorectal Cancer

Authors: Hussein S. Janabi, Zainab Lafi, Sina Matalqa

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8. Co-encapsulation of Coumarin and Q10 into Solid Lipid Nanoparticles for Wound Healing

Authors: Maisrh Ali Alrubaye, Zainab Lafi, Maha N. Abu Hajleh, Tamer M.M. Abuamara, Afnan Mehdawi

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9. Anticancer activity of liposomal formulation co-encapsulated with coumarin and phenyl butyric acid

Authors: Ali Allateef, Naeem Shalan, Zainab Lafi

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10. Analytical Approaches for Assessing Curcumin and Nicotinamide Co-Encapsulated in Liposomal Formulation: UV Spectrophotometry and HPLC Validation

Authors: Ali Fahdawi, Naeem Shalan, Zainab Lafi, Omar Markab

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11. Investigating anti-cancer activity of dual-loaded liposomes with thymoquinone and vitamin C

Authors: Ahmed Munef, Zainab Lafi, Naeem Shalan

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12. Formation and evaluation of doxorubicin and cromoglycate metal–organic framework for anti-cancer activity

Authors: Ebaa Abu Saleem, Zainab Lafi, Naeem Shalan, Walhan Alshaer, Imad Hamadneh

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13. Development of Pegylated NanoPhytosome Formulation with Oleuropein and Rutin to Compare AntiColonic Cancer Activity with Olea europaea Leaves Extract

Authors: Tabarek H. Mahmood, Ali Al-Samydai, Mazen Al Sulaibi, Moath Alqaraleh, Anas Ibrahim Abed, Naeem Shalan, Alaa Alsanabrah, Shrouq Taiseer Alsotari, Hamdi Nsairat, Walhan Alshaer

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14. Investigation of Enhancement Delivery of Camptothecin Through Hydroxy PropylβCyclodextrin Complexation, Loaded on PEGylated Rutin Liposomes

Authors: Rand Kareem Ahmed, Israa AlAni, Ali AlSamydai, Ali AlKinani

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15. CoLoaded Nanoparticles of Empagliflozin and Rutin for Pancreatitis Prevention and Anticancer Activity

Authors: Olla Maan, Ali Al-Samydai, Moath Alqaraleh, Hamdi Nsairat, Alaa Alsanabrah, Oriana Awwad, Yusuf Al-Hiari

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16. Investigating the Therapeutic Potential of Cisplatin and RutinLoaded Nanoliposomes Against Colorectal Cancer Cells

Authors: Abdulazeez M. Al-Mashhadani, Ali Al-Samydai, Ibrahim Al-Deeb, Simone Carradori, Hanan Azzam, Hussein S. Janabi, Dana Al Qudah, Walhan Alshaer and Marcel R. Mozafari

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17. Encapsulation of gingerol into nanoliposomes: Evaluation of in vitro antiinflammatory and anticancer activity

Authors: Fatima Alshaikh, Ali Al-Samydai, Reem Issa, Walhan Alshaer, Moath Alqaraleh, Lidia K. Al-Halaseh, Alaa Alsanabrah, Bayan Y. Ghanim, Khaldun M. Al Azzam, Nidal A. Qinna

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18. Preparation, Characterization, and Anticancer Activity of PEGylated Nano Liposomal Loaded with Rutin Against Human Carcinoma Cells (HT29)

Authors: Noorin Manhal Al-Ekaid, Ali Al-Samydai, Ibrahim Al-deeb, Hamdi Nsairat, Khaled Khleifat, Walhan Alshaer

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19. Preparation, characterization and wound-healing effect of PEGylated nanoliposomes loaded with oleuropein

Authors: Rand Alquraishi, Ali Al-samydai, Khaldun M. Al Azzam, Moath Alqaraleh, Lidia Al-Halaseh, Alaa Sanabrah, Maha N. Abu Hajleh, Arwa Al Khatib, Walhan Alsaher, El-Sayed Negim, Khaled Khleifat

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20. Telmisartan Enhances the Accumulation of Doxorubicin as a Combination Therapy for the Management of Triple Negative Breast Cancer

Authors: Wala’a Al-Safadi, Belal Omar Al-Najjar, Moath Alqaraleh, Anas Ibrahim Abed, Walhan Alshaer, Dana Alqudah, Fadwa Daoud, Razan Mohammad Obeidat, Obada Abdulmalek Sibai, Zainab Zaki Zakaraya

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21. Analgesic Effect of Neohesperidin is Mediated by TRPV1 Antagonism

Authors: Omar A. Abdulwahed, Belal O. Al-Najjar, Manal A. Abbas, Mohammad Alsalem

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22. Novel Glucokinase Activators: A Structure-Based Pharmacophore Modeling, QSAR Analysis, and Molecular Dynamics Approach

Authors: Mansour Al-Sayed Ahmad, Belal O. Al-Najjar, Ashok K. Shakya

URL: View Article

23. Cytotoxic, anti-inflammatory, antioxidant, and anti-glyoxalase-I evaluation of chelating substances: In silico and in vitro study

Authors: Mohammed Bashar Al-Qazzan, Qosay Al-Balas, Belal Alnajjar, Violet Kasabri, Yusuf Al-Hiari, Aref Zayed, Rema AlKhateeb, Mohammed Al-Akeedi

URL: View Article

24. Rhoifolin Potentiates the Anti-Cancer Activity of Doxorubicin in MDA-MB-231 Triple-Negative Breast Cancer Cells

Authors: Ahmad Saleh Al-Radaideh, Manal A. Abbas, Aya Y. Al-Kabariti, Moath Alqaraleh, Razan Madi, Razan Obeidat

URL: View Article

25. Codelivery of Raloxifene and Rutin as PEGylated Nanoliposomes: Formulation, Characterization, and Prophylactic Activity Against Breast Cancer

Authors: Maryam Abdulmaged Oleiwi, Ali Al-Samydai, Aya Y Al-Kabariti, Khaldun M Al Azzam, Simone Carradori, Walhan Alshaer

URL: View Article

Undergraduate Students

1. TRPC1 and TRPC5 in Colorectal Cancer: Mechanisms, Prognostic Markers, and Therapeutic Targets

Authors: Manal A. Abbas, Aya Y. Al-Kabariti, Randa El-Rayyes, Razan Obeidat, Abd-Alrahman Al-Rayyes

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2. QSAR, structure-based pharmacophore modelling and biological evaluation of novel platelet ADP receptor (P2Y12) antagonist

Authors: Belal O. Al-Najjar, Manal A. Abbas, Obada A. Sibai, Fadi G. Saqallah, Aya Y. Al-Kabariti

Link: View Article

3. Ononin’s Antagonistic Activity towards TRPV1: Insights from Molecular Dynamics and Capsaicin-Evoked Calcium Response in DRG Neurons

Authors: Fadi G. Saqallah, Manal A. Abbas, Belal O. Al-Najjar, Aya Y. Al-Kabariti, Muhammad Yusuf, Omar A. Abdulwahed, Noor A. Barakat, Mohammad Alsalem

Link: View Article

4. Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment

Authors: Zainab Lafi, Sina Matalqah, Ebaa Abu-Saleem, Nisreen Asha, Hala Mhaidat, Sherine Asha, Lara Al-Nashash, Hussein S. Janabi

Link: View Article

5. Analytical Approaches for Assessing Curcumin and Nicotinamide Co-Encapsulated in Liposomal Formulation: UV Spectrophotometry and HPLC Validation

Authors: Ali Fahdawi, Naeem Shalan, Zainab Lafi, Omar Markab

Link: View Article

6. CRISPR in clinical diagnostics: bridging the gap between research and practice

Authors: Zainab Lafi, Tha'er Ata, Sherine Asha

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7. The quandary of incorrect practice toward unused and expired pharmaceutical products in households

Authors: Ali Al-Samydai, Maha N. Abu Hajleh, Mahmood Al-Samydai, Lidia Kamal Al-Halaseh, Shahd Habash, Dania Alkhayyat, Sameera Abu Saef, Leen Haitham, Hadeel Sayel Bahloul, Majd Waleed Askender

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8. Social media’s contribution to increasing consumer awareness: An applied study on Instagram’s use among pharmacists

Authors: Enas Daoud, Ali Al-Samydai, Lidia K. Al-Halaseh, Ahmed S. A. Ali Agha, Tabark R. Al-Sammarraie, Zain Al-Tarawneh, Abdullah Aldulaimi, Fatimah Akram Othman, Rudaina Othman Yousif, Hany Akeel Al-Hussaniy

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9. Digital strategies intervention and impact in promoting health education and making health decisions among individuals

Authors: Ra’ed M. Shudifat, Ali Al-Samydai, Lidia Kamal Al-Halaseh, Sewar G. Shnaikat, Toqa Abu Aboud, Abdulazeez Alzuhairi, Mahmood Al-Samydai, Rudaina Othman Yousif

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10. Meta-analysis of nano-phytosomes: unleashing the potential of plant-derived compounds for advancing cancer therapy

Authors: Ali Al-Samydai, Hamdi Nsairat, Maha N Abu Hajleh, Bayan Aburas, Amal Akour, Tha'er Husam Ata, Tabarek H Mahmood, Tabarak Riyadh Al-Sammarraie, Rawan Atta, Rahaf Ali, Qasim Khalid Alazzawi, Ahmed Aburjai, Simone Carradori

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AI and innovative ecosystem research

1. Integrated Virtual Screening of Anthraquinone Derivatives for Anticancer Drug Discovery

Authors: Hui Ming Chua; Said Moshawih; Nurolaini Kifli; Hui Poh Goh; Long Chiau Ming; Khang Wen Goh

URL / DOI: View Article

2. Machine learning optimization of environmental factors influencing biomass and nutritional composition in local algal species

Authors: Aisha Khan; Saleem Ullah; Rifat Ali; Mahwish Rehman; Said Moshawih; Khang Wen Goh; Long Chiau Ming; Lai Ti Gew

URL / DOI: View Article

3. Applications of machine learning in liposomal formulation and development

Authors: Sina Matalqah; Zainab Lafi; Qasim Mhaidat; Nisreen Asha; Sara Yousef Asha

URL / DOI: View Article

4. A phytotherapeutic approach to hinder the resistance against clindamycin by MRSA: in vitro and in silico studies

Authors: Amal Mayyas; Ali Al-Samydai; Nehaya Al-Karablieh; Waleed A Zalloum; Deniz Al-Tawalbeh; Farah Al-Mamoori; Rula A Amr; Hamdi Al Nsairat; Simone Carradori; Lidia Kamal Al-Halaseh; Talal Aburjai

URL: View Article

5. Photocatalytic Polyaromatic hydrocarbons (PAH) utilizing magnetic CrFe2O4 nanoparticle: Green synthesis, characterization, ab initio studies, electronic, magnetic features and water treatment application

Authors: Afnan Al-Hunaiti; Asma M. Ghazzy; Nada T. Mahmoud

URL: View Article

6. Deciphering the Anti-Diabetic Potential of Gymnema Sylvestre Using Integrated Computer-Aided Drug Design and Network Pharmacology

Authors: Amal Mayyas; Ali Al-Samydai; Amjad Ibrahim Oraibi; Nawres Debbabi; Sara S. Hassan; Hany Aqeel Al-Hussainy; Ahmad Mohammad Salamatullah; Musaab Dauelbait; Mohammed Bourhia; Khalid S. Almaary

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7. Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation

Authors: Francesco Melfi; Marialuigia Fantacuzzi; Simone Carradori; Ilaria D'Agostino; Alessandra Ammazzalorso; Noemi Mencarelli; Marialucia Gallorini; Mattia Spano; Paolo Guglielmi; Mariangela Agamennone; Sazan Haji Ali; Ali Al-Samydai; Francesca Sisto

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8. Simvastatin inhibits 20-Hydroxyeicosatetraenoic acid formation: docking and in vitro assay

Authors: Yazun Jarrar; Mansour Almansour; Mansour Al-Sayed Ahmad; Belal O. Al-Najjar; Amin A. Al-Doaiss; Sireen Abdul Rahim Shilbayeh; Su-Jun Lee

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9. Phytochemical analysis, bioactivity, and molecular docking studies of Myrtus communis L. seeds and fruit peel extracts demonstrating antioxidant and anti-tyrosinase properties

Authors: Belal O. Al-Najjar; Fatma Elshibani; Mohamed A Sharkasi; Nouha El Shintiri; Esra El Naili; Munira Abdulsayid; Roya S. Abozayed; Hamdoon A. Mohammed

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10. Novel acridone derivatives as potential P2Y12 receptor inhibitors: integrating computational modeling and experimental analysis

Authors: Fadi G. Saqallah; Belal O. Al-Najjar; Aya Y. Al-Kabariti; Manal A. Abbas

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11. Synthesis, molecular docking, and antiinflammatory evaluation of novel 4-(benzo[d][1,3]dioxol-5-yloxy)-N,N-2-yn-1-amine derivatives as potent cysteinyl leukotriene receptor (CysLT2) antagonists

Authors: Areej M. Jaber; Mohammed M. Al-Mahadeen; Belal O. Al-Najjar; Raed A. Al-Qawasmeh

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12. Novel N-substituted Isatin-oxoindolin-1H-Benzo[D] Imidazole Fumarate as a New Class of JNK3 Inhibitor: Design, Synthesis, Molecular Modeling and its Biological Activity

Authors: Mohammed M. Al-Mahadeen; Areej M. Jaber; Belal O. Al-Najjar; Monther A. Khanfar; Mustafa M. El-Abadelah

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13. In-silico identification of 3,4-Diarylpyrazoles-based small molecules as potential Hsp90 inhibitors

Authors: Adam A. Aboalroub; Belal O. Al-Najjar

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14. Novel glucokinase activators: A structure-based pharmacophore modeling, QSAR analysis, and molecular dynamics approach

Authors: Mansour Al-Sayed Ahmad; Belal O. Al-Najjar; Ashok Shakya

URL: View Article